Denosyl Tablets

What is Denosyl? 
 
Denosyl is an anti-oxident that has been shown to increase hepatic Glutathione levels in the liver of dogs and cats. Glutathione is a potent antioxidant that protects the liver from toxins and death. Low liver glutathione concentrations are common in dogs and cats with decreased liver function. Denosyl’s activity goes far beyond just increasing Glutathione levels. It has been shown to protect liver cells from cell death and may be useful in cell repair and healing. S-Adenosylmethionine may also improve bile flow in cats. 
 
Denosyl is recommended to improve hepatic glutathione levels to help maintain and protect liver function. 45% of dogs and cats with liver problems have a low hepatic glutathione level. Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidant that protects hepatic cells.  
 
How is Denosyl Administered? 
 
For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. When giving more than one tablet, the total daily dose may be provided as a morning and evening dose. For example, a daily dose of three tablets could be divided into two tablets in the morning and one tablet in the evening. 
 
Daily administration is based on 20 mg of S-adenosylmethionine/kg bodyweight. Because the (enteric coated) tablet must be kept intact to prevent destruction by stomach acid, administration range is based on the nearest whole tablet.  
 
Tablets (90 mg) for cats & small dogs.  
Up to 5.9 kg bodyweight: 1 tablet.  
 
Tablets (225 mg) for medium dogs.  
6 to 15.9 kg: 1 tablet. 16 to 29.9 kg: 2 tablets  
(or 1 large (425 mg) tablet).  
 
Tablets (425 mg) for large dogs.  
16 to 29.9 kg: 1 tablet  
(or 2 medium (225 mg) tablets).  
30 to 54.9 kg: 2 tablets. Over 55 kg: 3 tablets.  
 
For optimal absorption, give tablets on an empty stomach, at least one hour before feeding. Administer a few millilitres of water immediately following any tablet administration to speed passage of the tablet into the stomach. For those owners who have difficulty administering tablets to their pets, Denosyl Tablets may be disguised in a small bite of food.